STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNPLA3Patatin like phospholipase domain containing 3. (543 aa)    
Predicted Functional Partners:
DGAT2
Diacylglycerol O-acyltransferase 2.
   
 
 0.930
PLPP5
Phospholipid phosphatase 5.
     
 0.923
LIPG
Lipase G, endothelial type.
   
 
 0.919
MOGAT2
Monoacylglycerol O-acyltransferase 2.
     
 0.909
MOGAT1
Monoacylglycerol O-acyltransferase 1.
     
 0.909
PNPLA2
PNPLA2/ATGL.
  
 
0.908
AGK
Acylglycerol kinase.
     
 0.908
PNLIPRP1
Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.
     
 0.906
LPL
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
   
 
  0.900
CEL
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
     
  0.900
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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