STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTC33Tetratricopeptide repeat domain 33. (304 aa)    
Predicted Functional Partners:
PMS1
HMG box domain-containing protein.
      
 0.841
RALGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS1; Guanine nucleotide exchange factor. May be involved in cytoskeletal organization.
      
 0.745
TMEM2
Alpha/beta hydrolase domain-containing protein 17B.
   
  
 0.740
AGR2
Anterior gradient 2, protein disulphide isomerase family member.
      
 0.703
GET4
Golgi to ER traffic protein 4 homolog; As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches- containing proteins in a soluble state and participates to their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of [...]
   
 
 0.692
LEO1
Uncharacterized protein.
    
 
 0.692
RARRES1
Ovocalyxin-32; Component of the matrix of the eggshell.
      
 0.589
GET3
Guided entry of tail-anchored proteins factor 3, ATPase.
   
 
 0.582
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
   
 
 0.572
RAD23A
RAD23 homolog A, nucleotide excision repair protein.
   
 
 0.572
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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