STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HAX1HCLS1 associated protein X-1. (315 aa)    
Predicted Functional Partners:
SGIP1
SH3 domain GRB2 like endophilin interacting protein 1.
      
 0.763
KRT222
IF rod domain-containing protein; Belongs to the intermediate filament family.
    
 
 0.762
PPIG
Peptidylprolyl isomerase G.
      
 0.742
FAM18B1
Golgi apparatus membrane protein TVP23 homolog.
      
 0.706
TMEM60
Uncharacterized protein.
      
 0.705
ATP1B3
Sodium/potassium-transporting ATPase subunit beta-3; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known; Belongs to the X(+)/potassium ATPases subunit beta family.
      
 0.600
PGM1
Uncharacterized protein; Belongs to the phosphohexose mutase family.
   
  
 0.589
SMU1
WD40 repeat-containing protein SMU1; Involved in pre-mRNA splicing as a component of the spliceosome (By similarity). Regulates alternative splicing of the HSPG2 pre-mRNA (By similarity). Required for normal accumulation of IK (By similarity). Required for normal mitotic spindle assembly and normal progress through mitosis (By similarity). Belongs to the WD repeat SMU1 family.
      
 0.583
CDH10
Cadherin-10; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
      
 0.583
PEX11B
Peroxisomal biogenesis factor 11 beta.
   
  
 0.537
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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