STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHID1Glyco_18 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (393 aa)    
Predicted Functional Partners:
SLC35B4
Solute carrier family 35 member B4.
      
 0.870
TIMM21
Translocase of inner mitochondrial membrane 21.
   
  
 0.785
CNDP1
Carnosine dipeptidase 1.
      
 0.784
PSAP
Prosaposin; The lysosomal degradation of sphingolipids takes place by the sequential action of specific hydrolases. Some of these enzymes require specific low-molecular mass, non-enzymic proteins: the sphingolipids activator proteins (coproteins). Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta- galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha- galactosidase A (EC 3.2.1.22). Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases.
     
 0.752
CNDP2
M20_dimer domain-containing protein.
   
  
 0.734
GUCY1A2
Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
      
 0.729
SLC35A3
Uncharacterized protein.
   
  
 0.715
UROD
Uroporphyrinogen decarboxylase.
      
 0.702
VMO1
Vitelline membrane outer layer protein 1; Exact function not known, component of the outer membrane of the vitelline layer of the egg. Seems to be able to synthesize N- acetylchito-oligosaccharides (n=14-15) from hexasaccharides of N- acetylglucosamine in a manner similar to the transferase activity of lysozyme; Belongs to the VMO1 family.
    
 
 0.657
WDR90
WD repeat domain 90.
    
 
 0.650
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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