STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SC5DSterol-C5-desaturase; Belongs to the sterol desaturase family. (442 aa)    
Predicted Functional Partners:
DHCR7
Uncharacterized protein.
   
 0.998
DHCR24
FAD-binding PCMH-type domain-containing protein.
  
 
 0.990
FDFT1
Uncharacterized protein.
  
 
 0.989
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 
 0.989
HSD17B7
Uncharacterized protein.
   
 0.984
LOC100857622
EXPERA domain-containing protein.
   
 
 0.979
C5H14orf1
Uncharacterized protein.
   
 
 0.970
CYP51A1
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 0.969
LBR
Delta(14)-sterol reductase LBR; Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis (By similarity). Anchors the lamina and the heterochromatin to the inner nuclear membrane (By similarity). Belongs to the ERG4/ERG24 family.
   
 0.960
MSMO1
Methylsterol monooxygenase 1; Catalyzes the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol; Belongs to the sterol desaturase family.
  
 
0.957
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.