STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAGI1Membrane associated guanylate kinase, WW and PDZ domain containing 1. (1416 aa)    
Predicted Functional Partners:
IGSF5
Immunoglobulin superfamily member 5.
    
 0.953
ACTN1
Alpha-actinin-1; F-actin cross-linking protein is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
    
 0.927
ACTN4
Alpha-actinin-4; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. Involved in tight junction assembly in epithelial cells. May also function as a transcriptional coactivator, stimulating transcription mediated by nuclear hormone receptors. Belongs to the alpha-actinin family.
    
 0.927
SYNPO
Synaptopodin.
     
  0.900
DENND4C
DENN domain containing 4C.
      
 0.781
RHBDF2
Rhomboid 5 homolog 2.
   
 
 0.761
DENND4A
DENN domain containing 4A.
      
 0.748
STAG1
SCD domain-containing protein.
      
 0.742
USP53
Ubiquitin specific peptidase 53.
   
 
 0.706
PLCE1
Phosphoinositide phospholipase C.
      
 0.679
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.