STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RIN3Ras and Rab interactor 3. (983 aa)    
Predicted Functional Partners:
BIN1
Uncharacterized protein.
    
 
 0.922
PPP4R3A
Protein phosphatase 4 regulatory subunit 3A.
      
 0.741
CD2AP
Uncharacterized protein.
    
 
 0.739
SORL1
Sortilin-related receptor; Sorting receptor that directs numerous proteins to their correct location within the cell. Along with AP-1 complex, involved Golgi apparatus - endosome sorting (By similarity). Sorting receptor for APP, regulating its intracellular trafficking and processing into amyloidogenic-beta peptides. Retains APP in the trans-Golgi network, hence preventing its transit through late endosomes where amyloid beta peptides Abeta40 and Abeta42 are generated (By similarity). Sorting receptor for the BDNF receptor NTRK2/TRKB that facilitates NTRK2 trafficking between synaptic [...]
      
 0.708
SPPL2A
PA domain-containing protein.
      
 0.706
CCDC91
Coiled-coil domain containing 91.
    
 
 0.702
CASS4
Cas scaffold protein family member 4.
   
  
 0.691
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
      
 0.630
CDCP2
CUB domain containing protein 2.
   
  
 0.611
PICALM
Phosphatidylinositol binding clathrin assembly protein.
      
 0.610
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.