STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHA6Pleckstrin homology domain containing A6. (1374 aa)    
Predicted Functional Partners:
GOLT1A
Golgi transport 1A.
 
    
 0.933
GOLT1B
Golgi transport 1B.
 
    
 0.888
ETNK2
Ethanolamine kinase 2.
      
 0.783
PIK3C2B
Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family.
   
  
 0.743
ETNK1
Ethanolamine kinase 1.
      
 0.708
PIK3CG
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
      
 0.673
GYS2
Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.
      
 0.618
LDHB
L-lactate dehydrogenase B chain; Belongs to the LDH/MDH superfamily. LDH family.
      
 0.486
RP2
Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as a GTPase-activating protein. May act as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins (By similarity); Belongs to the TBCC family.
      
 0.433
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.