STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CSTF2RRM domain-containing protein. (573 aa)    
Predicted Functional Partners:
CSTF1
Cleavage stimulation factor subunit 1.
    
 0.999
CSTF3
Suf domain-containing protein.
   
 0.999
PCF11
PCF11 cleavage and polyadenylation factor subunit.
    
 0.996
CPSF2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.994
CPSF3
Cleavage and polyadenylation specific factor 3.
   
 0.994
FIP1L1
Fip1 domain-containing protein.
   
 0.992
CPSF4
Uncharacterized protein.
   
 0.986
CLP1
Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Plays a role in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex: phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phospho [...]
   
 0.971
PAPOLB
Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.
    
 0.969
SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72; May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination; Belongs to the SSU72 phosphatase family.
   
 0.967
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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