STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAXDC2Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (335 aa)    
Predicted Functional Partners:
CYP51A1
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 0.947
SC5D
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 
 0.944
SQLE
SE domain-containing protein.
   
 
 0.926
HSD17B7
Uncharacterized protein.
   
 0.880
SIGMAR1
Sigma non-opioid intracellular receptor 1; May function in lipid transport from the endoplasmic reticulum and be involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. May regulate calcium efflux at the endoplasmic reticulum (By similarity).
   
 0.860
HSD3B1
3Beta_HSD domain-containing protein.
   
 0.848
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 
 0.846
FDFT1
Uncharacterized protein.
  
 
 0.833
C5H14orf1
Uncharacterized protein.
   
 
 0.825
RETSATL
Uncharacterized protein.
     
 0.815
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.