STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC426912Keratin. (121 aa)    
Predicted Functional Partners:
LOC110231148
Uncharacterized protein.
      
 0.763
EDCH3
Epidermal differentiation protein.
      
 0.763
POLR2C
RPOLD domain-containing protein.
   
 
 0.733
MLPH
RabBD domain-containing protein.
      
 0.702
COL23A1
Uncharacterized protein.
    
 
 0.617
SBNO2
Strawberry notch homolog 2.
      
 0.616
MYLKSML
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 
 0.611
AHCYL1
AdoHcyase_NAD domain-containing protein; Belongs to the adenosylhomocysteinase family.
      
 0.529
MYSM1
Histone H2A deubiquitinase MYSM1; Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation (By similarity).
    
 
 0.521
PTRF
Leucine zipper protein.
      
 0.481
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.