STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM63CTransmembrane protein 63C. (830 aa)    
Predicted Functional Partners:
SAMD4B
Sterile alpha motif domain containing 4B.
      
 0.871
GOLGA3
Golgin A3.
      
 0.851
TMEM87A
Transmembrane protein 87A.
      
 0.846
RNPC3
RNA binding region (RNP1, RRM) containing 3.
      
 0.843
R3HCC1
Uncharacterized protein.
      
 0.779
TMEM150C
Transmembrane protein 150C.
      
 0.745
TMEM120A
Transmembrane protein 120A.
      
 0.745
AP1G1
AP-1 complex subunit gamma.
   
 
 0.711
A2ML1
Uncharacterized protein.
      
 0.706
SORD
Sorbitol dehydrogenase; Polyol dehydrogenase that catalyzes the reversible NAD(+)- dependent oxidation of various sugar alcohols. Is active with D- sorbitol (D-glucitol) as substrate, leading to the C2-oxidized product D-fructose. Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism (By similarity).
   
  
 0.654
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.