STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
STY2533Putative membrane protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family. (125 aa)    
Predicted Functional Partners:
STY2532
Putative membrane protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family.
 
   
 0.976
pqaB
Melittin resistance protein PqaB; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the glycosyltransferase 83 family.
 
  
 0.972
STY2529
Putative lipopolysaccharide modification protein; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
 
  
 0.969
STY2530
Conserved hypothetical protein; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
 
    0.969
pmrF
Putative lipopolysaccharide modification protein; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
 
   
 0.927
STY2527
Putative lipopolysaccharide biosynthesis protein; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
 
  
 0.902
STY4020
Similar to Escherichia coli hypothetical 34.2 kDa protein in folX-hispP intergenic region. hypothetical 34.2 kda protein in folX-hispP intergenic region SW:YFCI_ECOLI (P77768) (296 aa) fasta scores: E(): 0, 64.5% id in 313 aa, and to Salmonella typhimurium hypothetical 35.3 kDa protein near tlpA operon SW:YTL2_SALTY (P37415) (313 aa) fasta scores: E(): 0, 56.1% id in 312 aa.
  
     0.654
STY4288
Similar to Escherichia coli hypothetical 34.9 kDa protein in glpC-ais intergenic region SW:YFAD_ECOLI (P37014) (299 aa) fasta scores: E(): 0, 63.7% id in 303 aa, and to Escherichia coli hypothetical 34.2 kDa protein in folX-hisP intergenic region SW:YFCI_ECOLI (P77768) (296 aa) fasta scores: E(): 0, 66.9% id in 308 aa.
  
     0.644
STY2456
Conserved hypothetical protein; Orthologue of E. coli yejG (YEJG_ECOLI); Fasta hit to YEJG_ECOLI (114 aa), 90% identity in 114 aa overlap.
  
     0.638
STY4875
Putative membrane protein; Similar to Escherichia coli hypothetical protein YfcI yfcI SW:YFCI_ECOLI (P77768) (296 aa) fasta scores: E(): 0, 62.6% id in 321 aa and to Salmonella typhimurium hypothetical protein near tlpA operon SW:YTL2_SALTY (P37415) (313 aa) fasta scores: E(): 0, 53.4% id in 320 aa.
  
     0.637
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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