STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purMPhosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00878. (339 aa)    
Predicted Functional Partners:
purN
Phosphoribosylglycinamide formyltransferase; Identified by match to protein family HMM PF00551; match to protein family HMM TIGR00639.
  
 0.999
EFQ58310.1
Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857.
 
 
 0.999
purD
Phosphoribosylamine--glycine ligase; Identified by match to protein family HMM PF01071; match to protein family HMM PF02222; match to protein family HMM PF02655; match to protein family HMM PF02843; match to protein family HMM PF02844; match to protein family HMM PF08442; match to protein family HMM TIGR00877.
 
 0.999
purF
Amidophosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM PF00310; match to protein family HMM TIGR01134.
 
 0.998
purC
Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Identified by match to protein family HMM PF01259; match to protein family HMM TIGR00081.
 
 
 0.993
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355.
 
  
 0.990
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162.
 
 
 0.990
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Identified by match to protein family HMM PF02222; match to protein family HMM TIGR01161.
 
 
 0.988
purB
Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928.
  
 
 0.931
thrB
Homoserine kinase; Identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR00191.
 
    
 0.908
Your Current Organism:
Streptococcus downei
NCBI taxonomy Id: 904293
Other names: S. downei F0415, Streptococcus downei F0415, Streptococcus downei str. F0415, Streptococcus downei strain F0415
Server load: low (6%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.