Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HMGCS23-hydroxy-3-methylglutaryl-CoA synthase 2. (504 aa)    
Predicted Functional Partners:
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase.
  
 
 0.995
ACAT1
acetyl-CoA acetyltransferase 1.
  
 0.989
ACAA2
acetyl-CoA acyltransferase 2.
  
 0.985
ACAT2
acetyl-CoA acetyltransferase 2.
  
 0.983
ACAA1
acetyl-CoA acyltransferase 1.
  
 0.981
ENSPSTP00000015460
annotation not available
  
 0.965
CARTPT
CART prepropeptide.
  
 0.965
EHHADH
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase.
  
 
 0.957
ENSPSTP00000022870
annotation not available
    
 0.957
FDPS
Farnesyl diphosphate synthase.
  
 
 0.955
Your Current Organism:
Pavo cristatus
NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl
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