MLH1 protein (Pavo cristatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

MLH1

mutL homolog 1. (387 aa)

Predicted Functional Partners:

PMS1

0.998

ENSPSTP00000008255

0.998

MLH3

0.998

PMS2

0.997

ENSPSTP00000002761

0.997

ENSPSTP00000018012

0.995

ENSPSTP00000018048

0.995

BLM

0.993

PCNA

0.993

BRIP1

0.992

Your Current Organism:

Pavo cristatus

NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLM	BRIP1	ENSPSTP00000006238	ENSPSTP00000016329	BLM RecQ like helicase.	BRCA1 interacting protein C-terminal helicase 1.	0.900
BLM	ENSPSTP00000002761	ENSPSTP00000006238	ENSPSTP00000002761	BLM RecQ like helicase.	annotation not available	0.547
BLM	ENSPSTP00000008255	ENSPSTP00000006238	ENSPSTP00000008255	BLM RecQ like helicase.	annotation not available	0.639
BLM	ENSPSTP00000018012	ENSPSTP00000006238	ENSPSTP00000018012	BLM RecQ like helicase.	annotation not available	0.934
BLM	ENSPSTP00000018048	ENSPSTP00000006238	ENSPSTP00000018048	BLM RecQ like helicase.	annotation not available	0.934
BLM	MLH1	ENSPSTP00000006238	ENSPSTP00000001095	BLM RecQ like helicase.	mutL homolog 1.	0.993
BLM	MLH3	ENSPSTP00000006238	ENSPSTP00000020405	BLM RecQ like helicase.	mutL homolog 3.	0.930
BLM	PCNA	ENSPSTP00000006238	ENSPSTP00000018659	BLM RecQ like helicase.	Proliferating cell nuclear antigen.	0.953
BLM	PMS1	ENSPSTP00000006238	ENSPSTP00000005760	BLM RecQ like helicase.	PMS1 homolog 1, mismatch repair system component.	0.482
BLM	PMS2	ENSPSTP00000006238	ENSPSTP00000001012	BLM RecQ like helicase.	PMS1 homolog 2, mismatch repair system component.	0.547
BRIP1	BLM	ENSPSTP00000016329	ENSPSTP00000006238	BRCA1 interacting protein C-terminal helicase 1.	BLM RecQ like helicase.	0.900
BRIP1	ENSPSTP00000002761	ENSPSTP00000016329	ENSPSTP00000002761	BRCA1 interacting protein C-terminal helicase 1.	annotation not available	0.976
BRIP1	ENSPSTP00000008255	ENSPSTP00000016329	ENSPSTP00000008255	BRCA1 interacting protein C-terminal helicase 1.	annotation not available	0.539
BRIP1	MLH1	ENSPSTP00000016329	ENSPSTP00000001095	BRCA1 interacting protein C-terminal helicase 1.	mutL homolog 1.	0.992
BRIP1	MLH3	ENSPSTP00000016329	ENSPSTP00000020405	BRCA1 interacting protein C-terminal helicase 1.	mutL homolog 3.	0.400
BRIP1	PCNA	ENSPSTP00000016329	ENSPSTP00000018659	BRCA1 interacting protein C-terminal helicase 1.	Proliferating cell nuclear antigen.	0.843
BRIP1	PMS1	ENSPSTP00000016329	ENSPSTP00000005760	BRCA1 interacting protein C-terminal helicase 1.	PMS1 homolog 1, mismatch repair system component.	0.846
BRIP1	PMS2	ENSPSTP00000016329	ENSPSTP00000001012	BRCA1 interacting protein C-terminal helicase 1.	PMS1 homolog 2, mismatch repair system component.	0.976
ENSPSTP00000002761	BLM	ENSPSTP00000002761	ENSPSTP00000006238	annotation not available	BLM RecQ like helicase.	0.547
ENSPSTP00000002761	BRIP1	ENSPSTP00000002761	ENSPSTP00000016329	annotation not available	BRCA1 interacting protein C-terminal helicase 1.	0.976