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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GIPC3GIPC PDZ domain containing family member 3. (172 aa)    
Predicted Functional Partners:
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 
 0.886
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 
 0.886
ANKRD24
Ankyrin repeat domain 24.
      
 0.651
RGS19
Regulator of G protein signaling 19.
    
 
 0.639
PLXND1
Plexin D1.
    
 
 0.631
GRXCR1
Glutaredoxin and cysteine rich domain containing 1.
   
  
 0.614
ESPN
Espin.
      
 0.584
FILIP1
Filamin A interacting protein 1.
      
 0.544
ENSPSTP00000026135
annotation not available
      
 0.536
NRP1
Neuropilin 1.
    
 
 0.510
Your Current Organism:
Pavo cristatus
NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.