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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARGpoly(ADP-ribose) glycohydrolase. (893 aa)    
Predicted Functional Partners:
PARP3
poly(ADP-ribose) polymerase family member 3.
    
 0.958
PARP1
poly(ADP-ribose) polymerase 1.
    
 0.955
PCNA
Proliferating cell nuclear antigen.
    
   0.905
ENSPSTP00000004237
annotation not available
    
 0.848
VWA5B2
Von Willebrand factor A domain containing 5B2.
    
 0.848
ENSPSTP00000022630
annotation not available
    
 0.848
FEN1
Flap structure-specific endonuclease 1.
     
 0.803
POLB
DNA polymerase beta.
     
 0.635
ENSPSTP00000002795
annotation not available
   
    0.631
ENSPSTP00000024945
annotation not available
   
    0.631
Your Current Organism:
Pavo cristatus
NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.