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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOK2Docking protein 2. (412 aa)    
Predicted Functional Partners:
TEK
TEK receptor tyrosine kinase.
    
 0.799
LCK
LCK proto-oncogene, Src family tyrosine kinase.
   
 0.779
TIE1
Tyrosine kinase with immunoglobulin like and EGF like domains 1.
    
 0.744
ENSPSTP00000007047
annotation not available
   
 
 0.743
HCK
HCK proto-oncogene, Src family tyrosine kinase.
   
 0.741
ENSPSTP00000023920
annotation not available
    
 0.713
RET
Ret proto-oncogene.
    
  0.693
ENSPSTP00000015813
annotation not available
    
  0.693
GFRA2
GDNF family receptor alpha 2.
     
 0.668
GRB2
Growth factor receptor bound protein 2.
    
 0.660
Your Current Organism:
Pavo cristatus
NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.