GEM protein (Pavo cristatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

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Co-expression

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[Homology]

Score

GEM

GTP binding protein overexpressed in skeletal muscle. (297 aa)

Predicted Functional Partners:

ENSPSTP00000005994

0.765

ENSPSTP00000025607

0.765

DOCK4

0.662

ITSN2

0.621

ENSPSTP00000018388

0.621

TSC2

0.592

FRMPD2

0.579

ENSPSTP00000004197

0.578

ENSPSTP00000024425

0.578

MST1R

0.573

Your Current Organism:

Pavo cristatus

NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DOCK4	GEM	ENSPSTP00000023075	ENSPSTP00000001398	Dedicator of cytokinesis 4.	GTP binding protein overexpressed in skeletal muscle.	0.662
ENSPSTP00000004197	GEM	ENSPSTP00000004197	ENSPSTP00000001398	annotation not available	GTP binding protein overexpressed in skeletal muscle.	0.578
ENSPSTP00000005994	ENSPSTP00000018388	ENSPSTP00000005994	ENSPSTP00000018388	annotation not available	annotation not available	0.703
ENSPSTP00000005994	ENSPSTP00000025607	ENSPSTP00000005994	ENSPSTP00000025607	annotation not available	annotation not available	0.815
ENSPSTP00000005994	GEM	ENSPSTP00000005994	ENSPSTP00000001398	annotation not available	GTP binding protein overexpressed in skeletal muscle.	0.765
ENSPSTP00000005994	ITSN2	ENSPSTP00000005994	ENSPSTP00000009929	annotation not available	Intersectin 2.	0.703
ENSPSTP00000018388	ENSPSTP00000005994	ENSPSTP00000018388	ENSPSTP00000005994	annotation not available	annotation not available	0.703
ENSPSTP00000018388	ENSPSTP00000025607	ENSPSTP00000018388	ENSPSTP00000025607	annotation not available	annotation not available	0.703
ENSPSTP00000018388	GEM	ENSPSTP00000018388	ENSPSTP00000001398	annotation not available	GTP binding protein overexpressed in skeletal muscle.	0.621
ENSPSTP00000018388	ITSN2	ENSPSTP00000018388	ENSPSTP00000009929	annotation not available	Intersectin 2.	0.972
ENSPSTP00000018388	MST1R	ENSPSTP00000018388	ENSPSTP00000000076	annotation not available	Macrophage stimulating 1 receptor.	0.443
ENSPSTP00000024425	GEM	ENSPSTP00000024425	ENSPSTP00000001398	annotation not available	GTP binding protein overexpressed in skeletal muscle.	0.578
ENSPSTP00000025607	ENSPSTP00000005994	ENSPSTP00000025607	ENSPSTP00000005994	annotation not available	annotation not available	0.815
ENSPSTP00000025607	ENSPSTP00000018388	ENSPSTP00000025607	ENSPSTP00000018388	annotation not available	annotation not available	0.703
ENSPSTP00000025607	GEM	ENSPSTP00000025607	ENSPSTP00000001398	annotation not available	GTP binding protein overexpressed in skeletal muscle.	0.765
ENSPSTP00000025607	ITSN2	ENSPSTP00000025607	ENSPSTP00000009929	annotation not available	Intersectin 2.	0.703
FRMPD2	GEM	ENSPSTP00000023709	ENSPSTP00000001398	FERM and PDZ domain containing 2.	GTP binding protein overexpressed in skeletal muscle.	0.579
GEM	DOCK4	ENSPSTP00000001398	ENSPSTP00000023075	GTP binding protein overexpressed in skeletal muscle.	Dedicator of cytokinesis 4.	0.662
GEM	ENSPSTP00000004197	ENSPSTP00000001398	ENSPSTP00000004197	GTP binding protein overexpressed in skeletal muscle.	annotation not available	0.578
GEM	ENSPSTP00000005994	ENSPSTP00000001398	ENSPSTP00000005994	GTP binding protein overexpressed in skeletal muscle.	annotation not available	0.765