Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CELSR3Cadherin EGF LAG seven-pass G-type receptor 3. (2998 aa)    
Predicted Functional Partners:
VANGL2
VANGL planar cell polarity protein 2.
    
 0.694
VANGL1
VANGL planar cell polarity protein 1.
    
 0.693
FZD6
Frizzled class receptor 6.
    
 0.568
INVS
Inversin.
    
 
 0.544
EFNB1
Ephrin B1.
      
 0.537
CHKA
Choline kinase alpha.
      
 0.488
ENSPSTP00000003273
annotation not available
      
 0.482
ENSPSTP00000009343
annotation not available
      
 0.482
ENSPSTP00000017702
annotation not available
      
 0.482
PRICKLE2
Prickle planar cell polarity protein 2.
   
 0.466
Your Current Organism:
Pavo cristatus
NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl
Server load: low (18%) [HD]