Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIRT5Sirtuin 5. (309 aa)    
Predicted Functional Partners:
SIRT6
Sirtuin 6.
  
0.970
SIRT7
Sirtuin 7.
   
 0.962
SIRT2
Sirtuin 2.
   
 0.960
SIRT3
Sirtuin 3.
  
0.956
SIRT4
Sirtuin 4.
  
 
0.941
CCAR1
Cell division cycle and apoptosis regulator 1.
    
 0.933
SIRT1
Sirtuin 1.
     
 0.930
WRN
WRN RecQ like helicase.
  
 
 0.922
ENSPSTP00000005133
annotation not available
     
 0.917
NADSYN1
NAD synthetase 1.
    
 0.914
Your Current Organism:
Pavo cristatus
NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl
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