close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIRT5Sirtuin 5. (309 aa)    
Predicted Functional Partners:
KDM2B
Lysine demethylase 2B.
    
 0.974
KDM2A
Lysine demethylase 2A.
    
 0.974
ENSPSTP00000020029
annotation not available
    
 0.974
NADSYN1
NAD synthetase 1.
    
 0.945
NADK
NAD kinase.
  
 
 0.943
ENSPSTP00000005133
annotation not available
     
 0.936
NMNAT1
Nicotinamide nucleotide adenylyltransferase 1.
   
 0.936
NUDT12
Nudix hydrolase 12.
    
 0.935
NMNAT3
Nicotinamide nucleotide adenylyltransferase 3.
   
 0.928
ENSPSTP00000009838
annotation not available
   
 0.917
Your Current Organism:
Pavo cristatus
NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.