Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PKMPyruvate kinase M1/2. (530 aa)    
Predicted Functional Partners:
ENO1
Enolase 1.
  
 0.990
PCK1
Phosphoenolpyruvate carboxykinase 1.
    
 0.990
ENO2
Enolase 2.
  
 0.984
LDHA
Lactate dehydrogenase A.
  
 0.983
ENO4
Enolase 4.
  
 0.982
ENSPSTP00000012187
annotation not available
  
 0.979
ENSPSTP00000004689
annotation not available
  
 0.976
ENSPSTP00000011762
annotation not available
  
 0.976
H6PD
Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.
  
 
 0.975
ENSPSTP00000002360
annotation not available
  
 0.967
Your Current Organism:
Pavo cristatus
NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl
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