Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GSRGlutathione-disulfide reductase. (460 aa)    
Predicted Functional Partners:
GPX4
Glutathione peroxidase 4.
   
 0.995
GPX8
Glutathione peroxidase 8 (putative).
   
 0.995
GPX1
Glutathione peroxidase 1.
   
 0.993
GPX2
Glutathione peroxidase 2.
   
 0.980
GPX3
Glutathione peroxidase 3.
   
 0.973
GSS
Glutathione synthetase.
   
 0.963
PRDX6
Peroxiredoxin 6.
  
 0.958
HPGDS
Hematopoietic prostaglandin D synthase.
   
 
 0.951
ENSPSTP00000012127
annotation not available
   
 0.947
ENSPSTP00000019099
annotation not available
   
 0.947
Your Current Organism:
Pavo cristatus
NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl
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