BEST4 protein (Pavo cristatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

BEST4

Bestrophin 4. (450 aa)

Predicted Functional Partners:

CA7

0.588

MERTK

0.543

ENSPSTP00000010511

0.504

GLUL

0.504

PDE6B

0.493

NRIP1

0.486

Your Current Organism:

Pavo cristatus

NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BEST4	CA7	ENSPSTP00000001934	ENSPSTP00000007274	Bestrophin 4.	Carbonic anhydrase 7.	0.588
BEST4	ENSPSTP00000010511	ENSPSTP00000001934	ENSPSTP00000010511	Bestrophin 4.	annotation not available	0.504
BEST4	GLUL	ENSPSTP00000001934	ENSPSTP00000023969	Bestrophin 4.	Glutamate-ammonia ligase.	0.504
BEST4	MERTK	ENSPSTP00000001934	ENSPSTP00000000963	Bestrophin 4.	MER proto-oncogene, tyrosine kinase.	0.543
BEST4	NRIP1	ENSPSTP00000001934	ENSPSTP00000013185	Bestrophin 4.	Nuclear receptor interacting protein 1.	0.486
BEST4	PDE6B	ENSPSTP00000001934	ENSPSTP00000022864	Bestrophin 4.	Phosphodiesterase 6B.	0.493
CA7	BEST4	ENSPSTP00000007274	ENSPSTP00000001934	Carbonic anhydrase 7.	Bestrophin 4.	0.588
ENSPSTP00000010511	BEST4	ENSPSTP00000010511	ENSPSTP00000001934	annotation not available	Bestrophin 4.	0.504
ENSPSTP00000010511	GLUL	ENSPSTP00000010511	ENSPSTP00000023969	annotation not available	Glutamate-ammonia ligase.	0.905
GLUL	BEST4	ENSPSTP00000023969	ENSPSTP00000001934	Glutamate-ammonia ligase.	Bestrophin 4.	0.504
GLUL	ENSPSTP00000010511	ENSPSTP00000023969	ENSPSTP00000010511	Glutamate-ammonia ligase.	annotation not available	0.905
MERTK	BEST4	ENSPSTP00000000963	ENSPSTP00000001934	MER proto-oncogene, tyrosine kinase.	Bestrophin 4.	0.543
NRIP1	BEST4	ENSPSTP00000013185	ENSPSTP00000001934	Nuclear receptor interacting protein 1.	Bestrophin 4.	0.486
NRIP1	PDE6B	ENSPSTP00000013185	ENSPSTP00000022864	Nuclear receptor interacting protein 1.	Phosphodiesterase 6B.	0.562
PDE6B	BEST4	ENSPSTP00000022864	ENSPSTP00000001934	Phosphodiesterase 6B.	Bestrophin 4.	0.493
PDE6B	NRIP1	ENSPSTP00000022864	ENSPSTP00000013185	Phosphodiesterase 6B.	Nuclear receptor interacting protein 1.	0.562