close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK5P21 (RAC1) activated kinase 5. (655 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.991
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.963
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.963
RAC2
Rac family small GTPase 2.
   
 0.961
ENSPSTP00000017905
annotation not available
    
 0.954
ENSPSTP00000021947
annotation not available
    
 0.954
ITSN2
Intersectin 2.
    
 0.948
ENSPSTP00000018388
annotation not available
    
 0.948
ENSPSTP00000000215
annotation not available
   
 0.946
RAC1
Rac family small GTPase 1.
   
 0.946
Your Current Organism:
Pavo cristatus
NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.