Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAK5P21 (RAC1) activated kinase 5. (655 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.992
PAK6
P21 (RAC1) activated kinase 6.
   
  0.974
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.952
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.952
INKA1
Inka box actin regulator 1.
    
 
 0.933
RAC2
Rac family small GTPase 2.
   
 0.932
PAK2
P21 (RAC1) activated kinase 2.
    
  0.924
ENSPSTP00000017905
annotation not available
    
 0.918
LIMK1
LIM domain kinase 1.
    
 0.918
ENSPSTP00000021947
annotation not available
    
 0.918
Your Current Organism:
Pavo cristatus
NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl
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