DES protein (Pavo cristatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

DES

Desmin. (435 aa)

Predicted Functional Partners:

ENSPSTP00000010078

0.924

VIM

0.800

UBAC1

0.690

CASP3

0.643

CENPU

0.643

ENSPSTP00000015537

0.643

MBP

0.616

CDH1

0.583

PVALB

0.574

ENSPSTP00000016641

0.574

Your Current Organism:

Pavo cristatus

NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP3	CDH1	ENSPSTP00000000931	ENSPSTP00000021814	Caspase 3.	Cadherin 1.	0.878
CASP3	DES	ENSPSTP00000000931	ENSPSTP00000003604	Caspase 3.	Desmin.	0.643
CASP3	ENSPSTP00000010078	ENSPSTP00000000931	ENSPSTP00000010078	Caspase 3.	annotation not available	0.665
CASP3	ENSPSTP00000015537	ENSPSTP00000000931	ENSPSTP00000015537	Caspase 3.	annotation not available	0.845
CASP3	MBP	ENSPSTP00000000931	ENSPSTP00000011854	Caspase 3.	Myelin basic protein.	0.616
CASP3	VIM	ENSPSTP00000000931	ENSPSTP00000023650	Caspase 3.	Vimentin.	0.643
CDH1	CASP3	ENSPSTP00000021814	ENSPSTP00000000931	Cadherin 1.	Caspase 3.	0.878
CDH1	CENPU	ENSPSTP00000021814	ENSPSTP00000014481	Cadherin 1.	Centromere protein U.	0.734
CDH1	DES	ENSPSTP00000021814	ENSPSTP00000003604	Cadherin 1.	Desmin.	0.583
CDH1	ENSPSTP00000015537	ENSPSTP00000021814	ENSPSTP00000015537	Cadherin 1.	annotation not available	0.824
CENPU	CDH1	ENSPSTP00000014481	ENSPSTP00000021814	Centromere protein U.	Cadherin 1.	0.734
CENPU	DES	ENSPSTP00000014481	ENSPSTP00000003604	Centromere protein U.	Desmin.	0.643
CENPU	ENSPSTP00000010078	ENSPSTP00000014481	ENSPSTP00000010078	Centromere protein U.	annotation not available	0.417
CENPU	VIM	ENSPSTP00000014481	ENSPSTP00000023650	Centromere protein U.	Vimentin.	0.643
DES	CASP3	ENSPSTP00000003604	ENSPSTP00000000931	Desmin.	Caspase 3.	0.643
DES	CDH1	ENSPSTP00000003604	ENSPSTP00000021814	Desmin.	Cadherin 1.	0.583
DES	CENPU	ENSPSTP00000003604	ENSPSTP00000014481	Desmin.	Centromere protein U.	0.643
DES	ENSPSTP00000010078	ENSPSTP00000003604	ENSPSTP00000010078	Desmin.	annotation not available	0.924
DES	ENSPSTP00000015537	ENSPSTP00000003604	ENSPSTP00000015537	Desmin.	annotation not available	0.643
DES	ENSPSTP00000016641	ENSPSTP00000003604	ENSPSTP00000016641	Desmin.	annotation not available	0.574