close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISCA1Iron-sulfur cluster assembly 1. (221 aa)    
Predicted Functional Partners:
ISCA2
Iron-sulfur cluster assembly 2.
  
 0.994
ISCU
Iron-sulfur cluster assembly enzyme.
  
  
 0.955
ENSPSTP00000001644
annotation not available
  
 
 0.898
SCLY
Selenocysteine lyase.
  
 
 0.886
NFU1
NFU1 iron-sulfur cluster scaffold.
  
 
 0.883
GLRX3
Glutaredoxin 3.
  
 0.880
IBA57
Iron-sulfur cluster assembly factor IBA57.
  
 
 0.865
TMEM14C
Transmembrane protein 14C.
      
 0.788
MOCOS
Molybdenum cofactor sulfurase.
  
 0.757
ENSPSTP00000005880
annotation not available
  
 
 0.744
Your Current Organism:
Pavo cristatus
NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.