Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAM12ADAM metallopeptidase domain 12. (902 aa)    
Predicted Functional Partners:
ADAM10
ADAM metallopeptidase domain 10.
     
 0.735
MERTK
MER proto-oncogene, tyrosine kinase.
    
  0.722
TYRO3
TYRO3 protein tyrosine kinase.
    
  0.613
ENSPSTP00000010492
annotation not available
     
 0.606
ENSPSTP00000019151
annotation not available
     
 0.606
SPAM1
Sperm adhesion molecule 1.
   
 
 0.601
CDH1
Cadherin 1.
    
 0.511
ENSPSTP00000002780
annotation not available
    
  0.481
ENSPSTP00000020503
annotation not available
    
  0.481
ENSPSTP00000025425
annotation not available
    
  0.481
Your Current Organism:
Pavo cristatus
NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl
Server load: low (20%) [HD]