Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TP53BP1Tumor protein p53 binding protein 1. (1675 aa)    
Predicted Functional Partners:
ENSPSTP00000003809
annotation not available
    
 0.997
CHEK2
Checkpoint kinase 2.
    
 0.992
ENSPSTP00000014972
annotation not available
    
 0.989
ENSPSTP00000014017
annotation not available
    
  0.987
BLM
BLM RecQ like helicase.
   
 
 0.986
TOPBP1
DNA topoisomerase II binding protein 1.
    
 
 0.986
ENSPSTP00000015013
annotation not available
    
 0.984
BRCA1
BRCA1 DNA repair associated.
    
 0.984
ENSPSTP00000018543
annotation not available
    
  0.982
XRCC6
X-ray repair cross complementing 6.
    
 0.980
Your Current Organism:
Pavo cristatus
NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.