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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMYD4SET and MYND domain containing 4. (681 aa)    
Predicted Functional Partners:
DOT1L
DOT1 like histone lysine methyltransferase.
    
 0.831
MTMR14
Myotubularin related protein 14.
     
 0.787
PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1.
   
  0.786
EHMT1
Euchromatic histone lysine methyltransferase 1.
     
 0.782
ENSPSTP00000017771
annotation not available
     
 0.772
ENSPSTP00000022486
annotation not available
   
 
0.755
SETD1B
SET domain containing 1B, histone lysine methyltransferase.
    
 0.743
KDM2B
Lysine demethylase 2B.
    
 0.738
KDM2A
Lysine demethylase 2A.
    
 0.738
ENSPSTP00000020029
annotation not available
    
 0.738
Your Current Organism:
Pavo cristatus
NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.