Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FURINFurin, paired basic amino acid cleaving enzyme. (789 aa)    
Predicted Functional Partners:
MMP15
Matrix metallopeptidase 15.
    
 0.904
MMP11
Matrix metallopeptidase 11.
    
 0.862
ENSPSTP00000000530
annotation not available
    
 0.860
NOTCH1
Notch receptor 1.
   
 0.848
ENSPSTP00000004432
annotation not available
    
 0.826
PDGFB
Platelet derived growth factor subunit B.
   
 
  0.819
PROS1
Protein S.
     
  0.814
FREM1
FRAS1 related extracellular matrix 1.
    
 0.794
ACE2
Angiotensin I converting enzyme 2.
      
 0.769
MMP17
Matrix metallopeptidase 17.
    
 0.734
Your Current Organism:
Pavo cristatus
NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.