SOST protein (Pavo cristatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

SOST

Sclerostin. (213 aa)

Predicted Functional Partners:

ENSPSTP00000009845

0.999

VRK3

0.928

MAPK1

0.886

MAPK7

0.886

ENSPSTP00000005266

0.842

ENSPSTP00000022744

0.842

MAPK10

0.828

MAPK13

0.828

MAPK14

0.828

ENSPSTP00000016801

0.828

Your Current Organism:

Pavo cristatus

NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPSTP00000005266	ENSPSTP00000016801	ENSPSTP00000005266	ENSPSTP00000016801	annotation not available	annotation not available	0.984
ENSPSTP00000005266	MAPK1	ENSPSTP00000005266	ENSPSTP00000011992	annotation not available	Mitogen-activated protein kinase 1.	0.437
ENSPSTP00000005266	MAPK10	ENSPSTP00000005266	ENSPSTP00000007546	annotation not available	Mitogen-activated protein kinase 10.	0.987
ENSPSTP00000005266	MAPK13	ENSPSTP00000005266	ENSPSTP00000007885	annotation not available	Mitogen-activated protein kinase 13.	0.834
ENSPSTP00000005266	MAPK14	ENSPSTP00000005266	ENSPSTP00000007905	annotation not available	Mitogen-activated protein kinase 14.	0.834
ENSPSTP00000005266	MAPK7	ENSPSTP00000005266	ENSPSTP00000017722	annotation not available	Mitogen-activated protein kinase 7.	0.437
ENSPSTP00000005266	SOST	ENSPSTP00000005266	ENSPSTP00000005899	annotation not available	Sclerostin.	0.842
ENSPSTP00000009845	SOST	ENSPSTP00000009845	ENSPSTP00000005899	annotation not available	Sclerostin.	0.999
ENSPSTP00000016801	ENSPSTP00000005266	ENSPSTP00000016801	ENSPSTP00000005266	annotation not available	annotation not available	0.984
ENSPSTP00000016801	ENSPSTP00000022744	ENSPSTP00000016801	ENSPSTP00000022744	annotation not available	annotation not available	0.984
ENSPSTP00000016801	MAPK1	ENSPSTP00000016801	ENSPSTP00000011992	annotation not available	Mitogen-activated protein kinase 1.	0.610
ENSPSTP00000016801	MAPK10	ENSPSTP00000016801	ENSPSTP00000007546	annotation not available	Mitogen-activated protein kinase 10.	0.831
ENSPSTP00000016801	MAPK13	ENSPSTP00000016801	ENSPSTP00000007885	annotation not available	Mitogen-activated protein kinase 13.	0.813
ENSPSTP00000016801	MAPK14	ENSPSTP00000016801	ENSPSTP00000007905	annotation not available	Mitogen-activated protein kinase 14.	0.826
ENSPSTP00000016801	MAPK7	ENSPSTP00000016801	ENSPSTP00000017722	annotation not available	Mitogen-activated protein kinase 7.	0.610
ENSPSTP00000016801	SOST	ENSPSTP00000016801	ENSPSTP00000005899	annotation not available	Sclerostin.	0.828
ENSPSTP00000022744	ENSPSTP00000016801	ENSPSTP00000022744	ENSPSTP00000016801	annotation not available	annotation not available	0.984
ENSPSTP00000022744	MAPK1	ENSPSTP00000022744	ENSPSTP00000011992	annotation not available	Mitogen-activated protein kinase 1.	0.437
ENSPSTP00000022744	MAPK10	ENSPSTP00000022744	ENSPSTP00000007546	annotation not available	Mitogen-activated protein kinase 10.	0.987
ENSPSTP00000022744	MAPK13	ENSPSTP00000022744	ENSPSTP00000007885	annotation not available	Mitogen-activated protein kinase 13.	0.834