Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CRB2Crumbs cell polarity complex component 2. (1165 aa)    
Predicted Functional Partners:
MSL2
MSL complex subunit 2.
    
 0.914
MAML1
Mastermind like transcriptional coactivator 1.
    
 0.843
ENSPSTP00000016456
annotation not available
    
 0.811
ENSPSTP00000016463
annotation not available
    
 0.811
NUMB
NUMB endocytic adaptor protein.
    
 0.796
NCSTN
Nicastrin.
    
 0.786
ENSPSTP00000009587
annotation not available
    
 0.719
DTX3L
Deltex E3 ubiquitin ligase 3L.
    
 0.703
DTX2
Deltex E3 ubiquitin ligase 2.
    
  0.702
KAT7
Lysine acetyltransferase 7.
    
 0.670
Your Current Organism:
Pavo cristatus
NCBI taxonomy Id: 9049
Other names: Indian peafowl, P. cristatus, blue peafowl
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