node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | L1IN56_GUITC | L1IPY4 | L1IN56 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Endo/exonuclease/phosphatase domain-containing protein. | 0.972 |
FEN1 | L1IPX8_GUITC | L1IPY4 | L1IPX8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family. | 0.865 |
FEN1 | L1IWX8_GUITC | L1IPY4 | L1IWX8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | ENDO3c domain-containing protein. | 0.513 |
FEN1 | L1IYE4_GUITC | L1IPY4 | L1IYE4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Nop domain-containing protein. | 0.549 |
FEN1 | L1JDP5_GUITC | L1IPY4 | L1JDP5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA ligase. | 0.865 |
FEN1 | L1JUN8_GUITC | L1IPY4 | L1JUN8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Lactamase_B domain-containing protein. | 0.978 |
FEN1 | L1JYD6_GUITC | L1IPY4 | L1JYD6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA_LIGASE_A3 domain-containing protein. | 0.978 |
L1IN56_GUITC | FEN1 | L1IN56 | L1IPY4 | Endo/exonuclease/phosphatase domain-containing protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.972 |
L1IN56_GUITC | L1IPX8_GUITC | L1IN56 | L1IPX8 | Endo/exonuclease/phosphatase domain-containing protein. | DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family. | 0.954 |
L1IN56_GUITC | L1IWX8_GUITC | L1IN56 | L1IWX8 | Endo/exonuclease/phosphatase domain-containing protein. | ENDO3c domain-containing protein. | 0.920 |
L1IN56_GUITC | L1IYE4_GUITC | L1IN56 | L1IYE4 | Endo/exonuclease/phosphatase domain-containing protein. | Nop domain-containing protein. | 0.957 |
L1IN56_GUITC | L1JDP5_GUITC | L1IN56 | L1JDP5 | Endo/exonuclease/phosphatase domain-containing protein. | DNA ligase. | 0.954 |
L1IN56_GUITC | L1JJD7_GUITC | L1IN56 | L1JJD7 | Endo/exonuclease/phosphatase domain-containing protein. | Uncharacterized protein. | 0.972 |
L1IN56_GUITC | L1JQ19_GUITC | L1IN56 | L1JQ19 | Endo/exonuclease/phosphatase domain-containing protein. | Nop domain-containing protein. | 0.955 |
L1IN56_GUITC | L1JUN8_GUITC | L1IN56 | L1JUN8 | Endo/exonuclease/phosphatase domain-containing protein. | Lactamase_B domain-containing protein. | 0.971 |
L1IN56_GUITC | L1JYD6_GUITC | L1IN56 | L1JYD6 | Endo/exonuclease/phosphatase domain-containing protein. | DNA_LIGASE_A3 domain-containing protein. | 0.971 |
L1IN56_GUITC | L1K2D8_GUITC | L1IN56 | L1K2D8 | Endo/exonuclease/phosphatase domain-containing protein. | Uncharacterized protein. | 0.988 |
L1IPX8_GUITC | FEN1 | L1IPX8 | L1IPY4 | DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.865 |
L1IPX8_GUITC | L1IN56_GUITC | L1IPX8 | L1IN56 | DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family. | Endo/exonuclease/phosphatase domain-containing protein. | 0.954 |
L1IPX8_GUITC | L1JDP5_GUITC | L1IPX8 | L1JDP5 | DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family. | DNA ligase. | 0.903 |