STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
L1ISR0_GUITCUncharacterized protein. (362 aa)    
Predicted Functional Partners:
L1IAY5_GUITC
A_deaminase domain-containing protein.
   
 
 0.928
L1JFJ0_GUITC
A_deaminase domain-containing protein.
   
 
 0.922
L1JMB6_GUITC
Nicotinamide-nucleotide adenylyltransferase.
     
 0.922
IMPDH
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
     
 0.912
GMPR
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
     
 0.912
L1ICV1_GUITC
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
     
 0.904
L1IDP9_GUITC
NAPRTase_N domain-containing protein.
     
 0.904
L1IRL0_GUITC
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
     
 0.904
L1JDW5_GUITC
Uncharacterized protein.
  
  
 
0.901
L1I9Z7_GUITC
Uncharacterized protein.
     
  0.900
Your Current Organism:
Guillardia theta
NCBI taxonomy Id: 905079
Other names: G. theta CCMP2712, Guillardia theta CCMP2712
Server load: low (26%) [HD]