L1ITA7_GUITC protein (Guillardia theta) - STRING interaction network

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L1ITA7_GUITC

Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (225 aa)

Predicted Functional Partners:

L1JC63_GUITC

0.905

PCNA

0.827

L1JGV3_GUITC

0.817

POLA4

0.743

L1JXX0_GUITC

0.743

POLE1

0.694

L1JJ17_GUITC

0.681

MCM7

0.664

TOP1

0.652

POLA1

0.642

Your Current Organism:

Guillardia theta

NCBI taxonomy Id: 905079
Other names: G. theta CCMP2712, Guillardia theta CCMP2712

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L1ITA7_GUITC	L1JC63_GUITC	L1ITA7	L1JC63	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.905
L1ITA7_GUITC	L1JGV3_GUITC	L1ITA7	L1JGV3	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	0.817
L1ITA7_GUITC	L1JJ17_GUITC	L1ITA7	L1JJ17	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	Helicase ATP-binding domain-containing protein.	0.681
L1ITA7_GUITC	L1JXX0_GUITC	L1ITA7	L1JXX0	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	Uncharacterized protein.	0.743
L1ITA7_GUITC	MCM7	L1ITA7	L1JGX3	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.664
L1ITA7_GUITC	PCNA	L1ITA7	L1IQM8	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.827
L1ITA7_GUITC	POLA1	L1ITA7	L1IL77	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	DNA polymerase.	0.642
L1ITA7_GUITC	POLA4	L1ITA7	L1IM64	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.743
L1ITA7_GUITC	POLE1	L1ITA7	L1ILX0	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.694
L1ITA7_GUITC	TOP1	L1ITA7	L1IU61	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	DNA topoisomerase I.	0.652
L1JC63_GUITC	L1ITA7_GUITC	L1JC63	L1ITA7	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.905
L1JC63_GUITC	L1JGV3_GUITC	L1JC63	L1JGV3	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.	0.817
L1JC63_GUITC	L1JJ17_GUITC	L1JC63	L1JJ17	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	Helicase ATP-binding domain-containing protein.	0.681
L1JC63_GUITC	L1JXX0_GUITC	L1JC63	L1JXX0	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	Uncharacterized protein.	0.743
L1JC63_GUITC	MCM7	L1JC63	L1JGX3	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.664
L1JC63_GUITC	PCNA	L1JC63	L1IQM8	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.827
L1JC63_GUITC	POLA1	L1JC63	L1IL77	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	DNA polymerase.	0.642
L1JC63_GUITC	POLA4	L1JC63	L1IM64	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.743
L1JC63_GUITC	POLE1	L1JC63	L1ILX0	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.694
L1JC63_GUITC	TOP1	L1JC63	L1IU61	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	DNA topoisomerase I.	0.652