TOP1 protein (Guillardia theta) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

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[Homology]

Score

TOP1

DNA topoisomerase I. (701 aa)

Predicted Functional Partners:

L1IZ52_GUITC

0.952

L1IQW8_GUITC

0.919

L1IRG4_GUITC

0.916

L1IY62_GUITC

0.916

L1J8D1_GUITC

0.916

L1J9U8_GUITC

0.916

SPT16

0.914

L1IF21_GUITC

0.913

L1JGF0_GUITC

0.886

POLE1

0.843

Your Current Organism:

Guillardia theta

NCBI taxonomy Id: 905079
Other names: G. theta CCMP2712, Guillardia theta CCMP2712

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L1IF21_GUITC	L1IRG4_GUITC	L1IF21	L1IRG4	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.770
L1IF21_GUITC	L1IY62_GUITC	L1IF21	L1IY62	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.770
L1IF21_GUITC	L1J8D1_GUITC	L1IF21	L1J8D1	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-like domain-containing protein.	0.999
L1IF21_GUITC	L1J9U8_GUITC	L1IF21	L1J9U8	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	TOP4c domain-containing protein.	0.770
L1IF21_GUITC	L1JGF0_GUITC	L1IF21	L1JGF0	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	SP-RING-type domain-containing protein.	0.998
L1IF21_GUITC	POLE1	L1IF21	L1ILX0	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.449
L1IF21_GUITC	TOP1	L1IF21	L1IU61	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	DNA topoisomerase I.	0.913
L1IQW8_GUITC	TOP1	L1IQW8	L1IU61	SWIB domain-containing protein.	DNA topoisomerase I.	0.919
L1IRG4_GUITC	L1IF21_GUITC	L1IRG4	L1IF21	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.770
L1IRG4_GUITC	L1IZ52_GUITC	L1IRG4	L1IZ52	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Uncharacterized protein.	0.431
L1IRG4_GUITC	L1J8D1_GUITC	L1IRG4	L1J8D1	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Ubiquitin-like domain-containing protein.	0.846
L1IRG4_GUITC	L1JGF0_GUITC	L1IRG4	L1JGF0	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	SP-RING-type domain-containing protein.	0.727
L1IRG4_GUITC	POLE1	L1IRG4	L1ILX0	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.510
L1IRG4_GUITC	TOP1	L1IRG4	L1IU61	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	DNA topoisomerase I.	0.916
L1IY62_GUITC	L1IF21_GUITC	L1IY62	L1IF21	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.770
L1IY62_GUITC	L1IZ52_GUITC	L1IY62	L1IZ52	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Uncharacterized protein.	0.431
L1IY62_GUITC	L1J8D1_GUITC	L1IY62	L1J8D1	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Ubiquitin-like domain-containing protein.	0.846
L1IY62_GUITC	L1JGF0_GUITC	L1IY62	L1JGF0	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	SP-RING-type domain-containing protein.	0.727
L1IY62_GUITC	POLE1	L1IY62	L1ILX0	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.510
L1IY62_GUITC	TOP1	L1IY62	L1IU61	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	DNA topoisomerase I.	0.916