L1IW02_GUITC protein (Guillardia theta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

L1IW02_GUITC

Uncharacterized protein. (706 aa)

Predicted Functional Partners:

L1ILA1_GUITC

0.998

L1J5R9_GUITC

0.971

L1JFK1_GUITC

0.959

L1JX19_GUITC

0.959

RPL23Ae

0.813

RPL31e

0.795

L1JL89_GUITC

0.726

L1J398_GUITC

0.653

RPL4e

0.650

RPL32e

0.610

Your Current Organism:

Guillardia theta

NCBI taxonomy Id: 905079
Other names: G. theta CCMP2712, Guillardia theta CCMP2712

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L1ILA1_GUITC	L1IW02_GUITC	L1ILA1	L1IW02	N-acetyltransferase domain-containing protein.	Uncharacterized protein.	0.998
L1ILA1_GUITC	L1J5R9_GUITC	L1ILA1	L1J5R9	N-acetyltransferase domain-containing protein.	Uncharacterized protein.	0.940
L1ILA1_GUITC	L1JFK1_GUITC	L1ILA1	L1JFK1	N-acetyltransferase domain-containing protein.	N-acetyltransferase domain-containing protein.	0.962
L1ILA1_GUITC	L1JL89_GUITC	L1ILA1	L1JL89	N-acetyltransferase domain-containing protein.	Uncharacterized protein.	0.611
L1ILA1_GUITC	L1JX19_GUITC	L1ILA1	L1JX19	N-acetyltransferase domain-containing protein.	N-acetyltransferase domain-containing protein.	0.962
L1ILA1_GUITC	RPL23Ae	L1ILA1	L1IGD0	N-acetyltransferase domain-containing protein.	Large subunit ribosomal protein L23Ae, cytoplasmic; Belongs to the universal ribosomal protein uL23 family.	0.824
L1ILA1_GUITC	RPL31e	L1ILA1	L1K1X1	N-acetyltransferase domain-containing protein.	Large subunit ribosomal protein L31e, cytoplasmic.	0.522
L1ILA1_GUITC	RPL32e	L1ILA1	L1JSF7	N-acetyltransferase domain-containing protein.	Large subunit ribosomal protein L32e, cytoplasmic.	0.598
L1ILA1_GUITC	RPL4e	L1ILA1	L1IKX5	N-acetyltransferase domain-containing protein.	Large subunit ribosomal protein L4e, cytoplasmic.	0.496
L1IW02_GUITC	L1ILA1_GUITC	L1IW02	L1ILA1	Uncharacterized protein.	N-acetyltransferase domain-containing protein.	0.998
L1IW02_GUITC	L1J398_GUITC	L1IW02	L1J398	Uncharacterized protein.	FPG_CAT domain-containing protein.	0.653
L1IW02_GUITC	L1J5R9_GUITC	L1IW02	L1J5R9	Uncharacterized protein.	Uncharacterized protein.	0.971
L1IW02_GUITC	L1JFK1_GUITC	L1IW02	L1JFK1	Uncharacterized protein.	N-acetyltransferase domain-containing protein.	0.959
L1IW02_GUITC	L1JL89_GUITC	L1IW02	L1JL89	Uncharacterized protein.	Uncharacterized protein.	0.726
L1IW02_GUITC	L1JX19_GUITC	L1IW02	L1JX19	Uncharacterized protein.	N-acetyltransferase domain-containing protein.	0.959
L1IW02_GUITC	RPL23Ae	L1IW02	L1IGD0	Uncharacterized protein.	Large subunit ribosomal protein L23Ae, cytoplasmic; Belongs to the universal ribosomal protein uL23 family.	0.813
L1IW02_GUITC	RPL31e	L1IW02	L1K1X1	Uncharacterized protein.	Large subunit ribosomal protein L31e, cytoplasmic.	0.795
L1IW02_GUITC	RPL32e	L1IW02	L1JSF7	Uncharacterized protein.	Large subunit ribosomal protein L32e, cytoplasmic.	0.610
L1IW02_GUITC	RPL4e	L1IW02	L1IKX5	Uncharacterized protein.	Large subunit ribosomal protein L4e, cytoplasmic.	0.650
L1J398_GUITC	L1IW02_GUITC	L1J398	L1IW02	FPG_CAT domain-containing protein.	Uncharacterized protein.	0.653

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

14

PPI enrichment p-value:

1.11e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:16489

Trafficking of myristoylated proteins to the cilium, and ADP-ribosylation factor-like protein 2/3

5 of 5

3.18

5.67

4.06e-11

CL:27900

Neuropeptide FF receptor family, and Orexin and neuropeptides FF and QRFP bind to their respective receptors

2 of 6

2.7

1.19

0.0069

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-5624138

Trafficking of myristoylated proteins to the cilium

3 of 4

3.05

2.7

1.26e-05

MAP-5620920

Cargo trafficking to the periciliary membrane

4 of 58

2.02

2.12

4.74e-05

MAP-5617833

Cilium Assembly

4 of 233

1.41

0.95

0.0068

MAP-1852241

Organelle biogenesis and maintenance

4 of 281

1.33

0.85

0.0106

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0342

GTP-binding

3 of 155

1.47

0.67

0.0414

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF05351

GMP-PDE, delta subunit

2 of 3

3.0

1.17

0.0077

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR044612

ADP-ribosylation factor-like protein 2/3

2 of 2

3.18

1.02

0.0145

IPR037036

GMP phosphodiesterase, delta subunit superfamily

2 of 3

3.0

1.02

0.0145

IPR008015

GMP phosphodiesterase, delta subunit

2 of 3

3.0

1.02

0.0145

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (26%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About