STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
L1IX50_GUITCTENA_THI-4 domain-containing protein. (226 aa)    
Predicted Functional Partners:
L1JZB6_GUITC
TENA_THI-4 domain-containing protein.
 
  
0.870
L1JH00_GUITC
Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...]
  
  
 0.736
L1JP81_GUITC
Uncharacterized protein.
  
  
 0.488
L1IU67_GUITC
SRP54 domain-containing protein.
  
  
 0.484
L1IW44_GUITC
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.478
TPK1
Putative TPK1/TPK2 thiamine Pyrophosphokinase.
     
 0.465
L1JUH6_GUITC
Rhodanese domain-containing protein.
     
 0.449
L1J9J9_GUITC
AA_kinase domain-containing protein.
     
 0.448
L1JCF3_GUITC
Pterin-binding domain-containing protein.
     
 0.447
L1I434_GUITC
ThiF domain-containing protein.
  
  
 0.439
Your Current Organism:
Guillardia theta
NCBI taxonomy Id: 905079
Other names: G. theta CCMP2712, Guillardia theta CCMP2712
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.