L1J470_GUITC protein (Guillardia theta) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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Score

L1J470_GUITC

Bac_surface_Ag domain-containing protein. (319 aa)

Predicted Functional Partners:

L1J700_GUITC

0.984

L1IB94_GUITC

0.958

L1J521_GUITC

0.912

L1JAF7_GUITC

0.912

L1IUZ3_GUITC

0.749

L1JC31_GUITC

0.749

L1ITP1_GUITC

0.696

L1I904_GUITC

0.665

L1IZB6_GUITC

0.665

L1JU10_GUITC

0.665

Your Current Organism:

Guillardia theta

NCBI taxonomy Id: 905079
Other names: G. theta CCMP2712, Guillardia theta CCMP2712

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L1I904_GUITC	L1IB94_GUITC	L1I904	L1IB94	Uncharacterized protein.	Uncharacterized protein.	0.874
L1I904_GUITC	L1J470_GUITC	L1I904	L1J470	Uncharacterized protein.	Bac_surface_Ag domain-containing protein.	0.665
L1I904_GUITC	L1J521_GUITC	L1I904	L1J521	Uncharacterized protein.	Uncharacterized protein.	0.442
L1I904_GUITC	L1J700_GUITC	L1I904	L1J700	Uncharacterized protein.	Uncharacterized protein.	0.525
L1I904_GUITC	L1JAF7_GUITC	L1I904	L1JAF7	Uncharacterized protein.	Uncharacterized protein; Belongs to the MICOS complex subunit Mic60 family.	0.442
L1IB94_GUITC	L1I904_GUITC	L1IB94	L1I904	Uncharacterized protein.	Uncharacterized protein.	0.874
L1IB94_GUITC	L1J470_GUITC	L1IB94	L1J470	Uncharacterized protein.	Bac_surface_Ag domain-containing protein.	0.958
L1IB94_GUITC	L1J521_GUITC	L1IB94	L1J521	Uncharacterized protein.	Uncharacterized protein.	0.686
L1IB94_GUITC	L1J700_GUITC	L1IB94	L1J700	Uncharacterized protein.	Uncharacterized protein.	0.992
L1IB94_GUITC	L1JAF7_GUITC	L1IB94	L1JAF7	Uncharacterized protein.	Uncharacterized protein; Belongs to the MICOS complex subunit Mic60 family.	0.686
L1IB94_GUITC	L1JU10_GUITC	L1IB94	L1JU10	Uncharacterized protein.	Uncharacterized protein.	0.874
L1ITP1_GUITC	L1IZB6_GUITC	L1ITP1	L1IZB6	FabA domain-containing protein.	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	0.759
L1ITP1_GUITC	L1J470_GUITC	L1ITP1	L1J470	FabA domain-containing protein.	Bac_surface_Ag domain-containing protein.	0.696
L1IUZ3_GUITC	L1J470_GUITC	L1IUZ3	L1J470	PDZ domain-containing protein.	Bac_surface_Ag domain-containing protein.	0.749
L1IZB6_GUITC	L1ITP1_GUITC	L1IZB6	L1ITP1	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	FabA domain-containing protein.	0.759
L1IZB6_GUITC	L1J470_GUITC	L1IZB6	L1J470	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	Bac_surface_Ag domain-containing protein.	0.665
L1J470_GUITC	L1I904_GUITC	L1J470	L1I904	Bac_surface_Ag domain-containing protein.	Uncharacterized protein.	0.665
L1J470_GUITC	L1IB94_GUITC	L1J470	L1IB94	Bac_surface_Ag domain-containing protein.	Uncharacterized protein.	0.958
L1J470_GUITC	L1ITP1_GUITC	L1J470	L1ITP1	Bac_surface_Ag domain-containing protein.	FabA domain-containing protein.	0.696
L1J470_GUITC	L1IUZ3_GUITC	L1J470	L1IUZ3	Bac_surface_Ag domain-containing protein.	PDZ domain-containing protein.	0.749

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Network Stats

number of nodes:

7

number of edges:

11

average node degree:

3.14

avg. local clustering coefficient:

0.833

expected number of edges:

7

PPI enrichment p-value:

0.119

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030170

Pyridoxal phosphate binding

4 of 75

1.95

2.16

0.00011

GO:0003870

5-aminolevulinate synthase activity

2 of 2

3.22

1.99

0.00081

GO:0016747

Acyltransferase activity, transferring groups other than amino-acyl groups

3 of 161

1.49

0.89

0.0210

GO:0016740

Transferase activity

5 of 1261

0.82

0.47

0.0462

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0017059

Serine C-palmitoyltransferase complex

2 of 2

3.22

1.82

0.0015

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:32476782

(2020) Natural products that target macrophages in treating non-alcoholic steatohepatitis.

2 of 2

3.22

2.34

0.00023

PMID:24220500

(2014) The yeast sphingolipid signaling landscape.

2 of 6

2.75

2.07

0.00054

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

ela00600

Sphingolipid metabolism

2 of 30

2.05

1.23

0.0090

ela04138

Autophagy - yeast

2 of 58

1.76

0.97

0.0212

ela01100

Metabolic pathways

6 of 1189

0.93

0.79

0.00086

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-189451

Heme biosynthesis

2 of 13

2.41

0.96

0.0302

MAP-189445

Metabolism of porphyrins

2 of 14

2.38

0.96

0.0302

MAP-5661270

Formation of xylulose-5-phosphate

2 of 30

2.05

0.82

0.0474

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0017059

Serine C-palmitoyltransferase complex

2 of 2

3.22

1.77

0.0018

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0808

Transferase

5 of 868

0.98

0.69

0.0103

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00155

Aminotransferase class I and II

3 of 18

2.44

2.3

0.00018

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR004839

Aminotransferase, class I/classII

4 of 18

2.57

3.65

9.59e-07

IPR015422

Pyridoxal phosphate-dependent transferase, small domain

4 of 45

2.17

2.77

1.38e-05

IPR015424

Pyridoxal phosphate-dependent transferase

4 of 58

2.06

2.58

2.26e-05

IPR015421

Pyridoxal phosphate-dependent transferase, major domain

4 of 57

2.07

2.58

2.26e-05

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