STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
L1J7V6_GUITC3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (471 aa)    
Predicted Functional Partners:
L1I9G1_GUITC
Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.999
L1J037_GUITC
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.997
L1I9V4_GUITC
Uncharacterized protein.
  
  
 0.987
L1IBX5_GUITC
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.979
L1I8R9_GUITC
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
 
 
 0.956
L1J501_GUITC
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.937
L1JLF2_GUITC
Mevalonate kinase.
  
  
 0.903
L1IUN2_GUITC
P450 superfamily protein; Belongs to the cytochrome P450 family.
  
 
 0.892
L1JR66_GUITC
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
     
 0.881
L1J8U4_GUITC
Citrate synthase; Belongs to the citrate synthase family.
    
 0.857
Your Current Organism:
Guillardia theta
NCBI taxonomy Id: 905079
Other names: G. theta CCMP2712, Guillardia theta CCMP2712
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.