node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EXO1 | FEN1 | L1JXH0 | L1IPY4 | EXO1 exonuclease 1 DNA repair. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.745 |
EXO1 | L1IHN9_GUITC | L1JXH0 | L1IHN9 | EXO1 exonuclease 1 DNA repair. | WD_REPEATS_REGION domain-containing protein. | 0.819 |
EXO1 | L1ILS4_GUITC | L1JXH0 | L1ILS4 | EXO1 exonuclease 1 DNA repair. | Uncharacterized protein. | 0.905 |
EXO1 | L1IPZ0_GUITC | L1JXH0 | L1IPZ0 | EXO1 exonuclease 1 DNA repair. | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | 0.873 |
EXO1 | L1J0R3_GUITC | L1JXH0 | L1J0R3 | EXO1 exonuclease 1 DNA repair. | 3'-5' exonuclease domain-containing protein. | 0.996 |
EXO1 | L1JI47_GUITC | L1JXH0 | L1JI47 | EXO1 exonuclease 1 DNA repair. | AAA_12 domain-containing protein. | 0.936 |
EXO1 | L1JJD7_GUITC | L1JXH0 | L1JJD7 | EXO1 exonuclease 1 DNA repair. | Uncharacterized protein. | 0.745 |
EXO1 | L1JRL3_GUITC | L1JXH0 | L1JRL3 | EXO1 exonuclease 1 DNA repair. | ANK_REP_REGION domain-containing protein. | 0.882 |
EXO1 | RPA1 | L1JXH0 | L1IC32 | EXO1 exonuclease 1 DNA repair. | Replication protein A subunit. | 0.750 |
EXO1 | RPA1-2 | L1JXH0 | L1IGL0 | EXO1 exonuclease 1 DNA repair. | Replication protein A subunit. | 0.750 |
FEN1 | EXO1 | L1IPY4 | L1JXH0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | EXO1 exonuclease 1 DNA repair. | 0.745 |
FEN1 | L1IHN9_GUITC | L1IPY4 | L1IHN9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | WD_REPEATS_REGION domain-containing protein. | 0.677 |
FEN1 | L1ILS4_GUITC | L1IPY4 | L1ILS4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.745 |
FEN1 | L1IPZ0_GUITC | L1IPY4 | L1IPZ0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | 0.731 |
FEN1 | L1J0R3_GUITC | L1IPY4 | L1J0R3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 3'-5' exonuclease domain-containing protein. | 0.998 |
FEN1 | L1JI47_GUITC | L1IPY4 | L1JI47 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | AAA_12 domain-containing protein. | 0.955 |
FEN1 | L1JRL3_GUITC | L1IPY4 | L1JRL3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | ANK_REP_REGION domain-containing protein. | 0.713 |
FEN1 | RPA1 | L1IPY4 | L1IC32 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Replication protein A subunit. | 0.705 |
FEN1 | RPA1-2 | L1IPY4 | L1IGL0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Replication protein A subunit. | 0.705 |
L1IHN9_GUITC | EXO1 | L1IHN9 | L1JXH0 | WD_REPEATS_REGION domain-containing protein. | EXO1 exonuclease 1 DNA repair. | 0.819 |