node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
L1ITU4_GUITC | L1IZJ7_GUITC | L1ITU4 | L1IZJ7 | RF_PROK_I domain-containing protein. | Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. | 0.469 |
L1ITU4_GUITC | L1J0F3_GUITC | L1ITU4 | L1J0F3 | RF_PROK_I domain-containing protein. | TruB_N domain-containing protein. | 0.517 |
L1ITU4_GUITC | L1JGV3_GUITC | L1ITU4 | L1JGV3 | RF_PROK_I domain-containing protein. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.519 |
L1ITU4_GUITC | L1JPQ1_GUITC | L1ITU4 | L1JPQ1 | RF_PROK_I domain-containing protein. | Uncharacterized protein. | 0.604 |
L1IW44_GUITC | L1IZJ7_GUITC | L1IW44 | L1IZJ7 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. | 0.561 |
L1IW44_GUITC | L1J7H2_GUITC | L1IW44 | L1J7H2 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.409 |
L1IW44_GUITC | L1JGV3_GUITC | L1IW44 | L1JGV3 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.670 |
L1IW44_GUITC | L1JPQ1_GUITC | L1IW44 | L1JPQ1 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | Uncharacterized protein. | 0.878 |
L1IW44_GUITC | L1K252_GUITC | L1IW44 | L1K252 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.617 |
L1IZJ7_GUITC | L1ITU4_GUITC | L1IZJ7 | L1ITU4 | Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. | RF_PROK_I domain-containing protein. | 0.469 |
L1IZJ7_GUITC | L1IW44_GUITC | L1IZJ7 | L1IW44 | Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.561 |
L1IZJ7_GUITC | L1J7H2_GUITC | L1IZJ7 | L1J7H2 | Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.716 |
L1IZJ7_GUITC | L1JGQ3_GUITC | L1IZJ7 | L1JGQ3 | Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. | Uncharacterized protein. | 0.456 |
L1IZJ7_GUITC | L1JGV3_GUITC | L1IZJ7 | L1JGV3 | Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.704 |
L1IZJ7_GUITC | L1JNM4_GUITC | L1IZJ7 | L1JNM4 | Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. | Uncharacterized protein. | 0.595 |
L1IZJ7_GUITC | L1JPQ1_GUITC | L1IZJ7 | L1JPQ1 | Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. | Uncharacterized protein. | 0.708 |
L1IZV8_GUITC | L1JGV3_GUITC | L1IZV8 | L1JGV3 | CHCH domain-containing protein. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.684 |
L1IZV8_GUITC | L1JPQ1_GUITC | L1IZV8 | L1JPQ1 | CHCH domain-containing protein. | Uncharacterized protein. | 0.546 |
L1J0F3_GUITC | L1ITU4_GUITC | L1J0F3 | L1ITU4 | TruB_N domain-containing protein. | RF_PROK_I domain-containing protein. | 0.517 |
L1J0F3_GUITC | L1JPQ1_GUITC | L1J0F3 | L1JPQ1 | TruB_N domain-containing protein. | Uncharacterized protein. | 0.546 |