STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bin3Top6B/Bin3 vegetative topoisomerase VIB. (617 aa)    
Predicted Functional Partners:
Spo11-1
Meiosis-specific transesterase.
  
 
 0.986
L1IU04_GUITC
Topoisomerase 6 subunit A.
 
 
 0.982
L1JZ56_GUITC
Translation initiation factor 2, alpha subunit.
   
 
 0.692
L1JAA9_GUITC
Uncharacterized protein.
  
   
 0.622
ORC1
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
  
 0.617
POLA4
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
      
 0.602
L1IMX7_GUITC
Uncharacterized protein.
     
 0.602
L1J5P4_GUITC
Uncharacterized protein.
  
  
 0.589
RPS8e
40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family.
 
      0.568
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
      
 0.550
Your Current Organism:
Guillardia theta
NCBI taxonomy Id: 905079
Other names: G. theta CCMP2712, Guillardia theta CCMP2712
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.