STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
L1JSB6_GUITCFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (344 aa)    
Predicted Functional Partners:
L1JK92_GUITC
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
   
 
 0.925
L1JX35_GUITC
Sterol desaturase; Belongs to the sterol desaturase family.
   
 
 0.925
L1IUQ4_GUITC
Cytochrome b5 heme-binding domain-containing protein.
   
0.843
L1J5B8_GUITC
Uncharacterized protein.
 
      0.832
L1IMI0_GUITC
Uncharacterized protein.
   
 
 0.808
L1JVE4_GUITC
Sterol desaturase; Belongs to the sterol desaturase family.
   
 
 0.808
L1JFF5_GUITC
Aldedh domain-containing protein.
    
 0.803
L1ITG1_GUITC
Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.
   
 
 0.751
L1IUN2_GUITC
P450 superfamily protein; Belongs to the cytochrome P450 family.
   
 
 0.734
L1JF55_GUITC
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
   
  
 0.709
Your Current Organism:
Guillardia theta
NCBI taxonomy Id: 905079
Other names: G. theta CCMP2712, Guillardia theta CCMP2712
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