STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POLD1-2DNA polymerase. (985 aa)    
Predicted Functional Partners:
POLD2
DNA polymerase delta small subunit.
   
 0.997
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.972
POLE2
DNA polymerase epsilon subunit B.
   
 0.970
POLD4
DNA polymerase delta subunit 4.
    
 0.970
POLA4
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
  
 0.960
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.952
MCM5
DNA helicase; Belongs to the MCM family.
   
 0.948
POLA2
DNA polymerase alpha subunit B.
   
 0.943
L1JJ17_GUITC
Helicase ATP-binding domain-containing protein.
  
 0.938
MCM2
DNA helicase; Belongs to the MCM family.
   
 0.937
Your Current Organism:
Guillardia theta
NCBI taxonomy Id: 905079
Other names: G. theta CCMP2712, Guillardia theta CCMP2712
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