STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
L1JU69_GUITCNudix hydrolase domain-containing protein. (111 aa)    
Predicted Functional Partners:
L1JGV3_GUITC
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
     
 0.754
L1K0Z3_GUITC
Nudix hydrolase domain-containing protein.
  
  
 0.683
mutYH
MutYH base excision repair protein.
  
  
 0.679
L1IRC8_GUITC
Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
  
 0.668
L1J5U7_GUITC
Exonuclease domain-containing protein.
     
 0.647
L1JMB6_GUITC
Nicotinamide-nucleotide adenylyltransferase.
  
  
 0.637
L1INU7_GUITC
GTP_cyclohydroI domain-containing protein.
  
  
 0.630
L1IIS2_GUITC
ATP-grasp domain-containing protein.
     
 0.627
L1IAH1_GUITC
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.619
L1JCF3_GUITC
Pterin-binding domain-containing protein.
     
 0.616
Your Current Organism:
Guillardia theta
NCBI taxonomy Id: 905079
Other names: G. theta CCMP2712, Guillardia theta CCMP2712
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