node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EXO1 | FEN1 | L1JXH0 | L1IPY4 | EXO1 exonuclease 1 DNA repair. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.745 |
EXO1 | L1I9Y3_GUITC | L1JXH0 | L1I9Y3 | EXO1 exonuclease 1 DNA repair. | Helicase ATP-binding domain-containing protein. | 0.624 |
EXO1 | L1ILS4_GUITC | L1JXH0 | L1ILS4 | EXO1 exonuclease 1 DNA repair. | Uncharacterized protein. | 0.905 |
EXO1 | L1IRY2_GUITC | L1JXH0 | L1IRY2 | EXO1 exonuclease 1 DNA repair. | Uncharacterized protein. | 0.624 |
EXO1 | L1JI48_GUITC | L1JXH0 | L1JI48 | EXO1 exonuclease 1 DNA repair. | Uncharacterized protein. | 0.587 |
EXO1 | L1JJ17_GUITC | L1JXH0 | L1JJ17 | EXO1 exonuclease 1 DNA repair. | Helicase ATP-binding domain-containing protein. | 0.910 |
EXO1 | L1JJD7_GUITC | L1JXH0 | L1JJD7 | EXO1 exonuclease 1 DNA repair. | Uncharacterized protein. | 0.745 |
EXO1 | L1JW71_GUITC | L1JXH0 | L1JW71 | EXO1 exonuclease 1 DNA repair. | POLAc domain-containing protein. | 0.624 |
EXO1 | Mre11 | L1JXH0 | L1JFY3 | EXO1 exonuclease 1 DNA repair. | Mre11/sbcD nuclease. | 0.978 |
EXO1 | Rad50 | L1JXH0 | L1J1X1 | EXO1 exonuclease 1 DNA repair. | Rad50/sbcC double strand break DNA repair processing nuclease, meiosis and mitosis. | 0.877 |
FEN1 | EXO1 | L1IPY4 | L1JXH0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | EXO1 exonuclease 1 DNA repair. | 0.745 |
FEN1 | L1I9Y3_GUITC | L1IPY4 | L1I9Y3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Helicase ATP-binding domain-containing protein. | 0.591 |
FEN1 | L1ILS4_GUITC | L1IPY4 | L1ILS4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.745 |
FEN1 | L1IRY2_GUITC | L1IPY4 | L1IRY2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.591 |
FEN1 | L1JI48_GUITC | L1IPY4 | L1JI48 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.428 |
FEN1 | L1JJ17_GUITC | L1IPY4 | L1JJ17 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Helicase ATP-binding domain-containing protein. | 0.909 |
FEN1 | L1JW71_GUITC | L1IPY4 | L1JW71 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | POLAc domain-containing protein. | 0.591 |
FEN1 | Mre11 | L1IPY4 | L1JFY3 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Mre11/sbcD nuclease. | 0.968 |
FEN1 | Rad50 | L1IPY4 | L1J1X1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Rad50/sbcC double strand break DNA repair processing nuclease, meiosis and mitosis. | 0.955 |
L1I9Y3_GUITC | EXO1 | L1I9Y3 | L1JXH0 | Helicase ATP-binding domain-containing protein. | EXO1 exonuclease 1 DNA repair. | 0.624 |