Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
METMET proto-oncogene, receptor tyrosine kinase. (1382 aa)    
Predicted Functional Partners:
HGF
Hepatocyte growth factor.
    
 0.999
GAB1
GRB2 associated binding protein 1.
    
 0.997
GRB2
Growth factor receptor bound protein 2.
    
 0.997
CBL
Cbl proto-oncogene.
    
 0.993
LRIG1
Leucine rich repeats and immunoglobulin like domains 1.
    
 0.986
PTPN1
Protein tyrosine phosphatase non-receptor type 1.
    
 0.973
MST1
Macrophage stimulating 1.
    
 0.956
CTNNB1
Catenin beta 1.
    
 0.954
PLXNB1
Plexin B1.
    
 
0.945
PLXNB2
Plexin B2.
    
 
0.945
Your Current Organism:
Phasianus colchicus
NCBI taxonomy Id: 9054
Other names: P. colchicus, Ring-necked pheasant, common pheasant
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